Overview

Our initial assessment is that glycol vapors could be affordable, effective, and rapidly deployed as an additional layer of defense during outbreaks of airborne-transmissible pathogens. Studies that build on the existing evidence base could help further evaluate the potential for glycol vapors to be used as a response intervention during future infectious disease emergencies. The aim of this Request for Proposals is to inform evidence-based guidance for incorporating glycol vapor air disinfection into comprehensive pandemic preparedness and response strategies.

Opportunity

Read the full RFP here.

We invite 1-4 page Expressions of Interest from groups interested in investigating the following areas:

1. Mechanisms of pathogen inactivation
2. Efficacy during emergency deployment
3. Interactions of glycol vapors with filtration media
4. Human safety, especially in potentially-sensitive persons or groups
5. Real-world field observation
6. Additional studies

We welcome submissions from all teams who are experts in microbiology or indoor air, no matter your level of prior experience with glycol vapors. We encourage you to submit an Expression of Interest if you believe you can deliver on the objectives of one or more of the areas above, even if you have no prior experience with glycol vapors. Please reach out to glycoliser@blueprintbiosecurity.org if you have questions about glycol vapors or study requirements; we are happy to help.

Anticipated awards

A single proposer may (but does not need to) submit a proposal addressing multiple technical areas, and we encourage multiple groups to form teams where appropriate. We have included expected proposal values for each technical area; these guidelines represent our best estimate for the maximum amount that a study answering the key questions might cost if run efficiently. 

Depending on proposal quality, cost-effectiveness, and available funding, we may not make an award for every technical area, or we may make multiple awards in some technical areas and none in others. Potential awards range from $100k-$1.4m per technical area. 

We particularly value speed of execution, and we have a preference for proposals that reasonably aim to achieve their stated deliverables within 12 months or sooner.

Important dates

Posting date: September 22, 2025.

Final deadline for Expressions of Interest: October 24, 2025 (11:59pm PT). 

Expressions of Interest will be evaluated on a rolling basis. Selected groups will then be invited to submit a Full Proposal within 3 weeks after Notice of Recommendation.

Submission instructions

Please email submissions to glycoliser@blueprintbiosecurity.org.

Submissions are encouraged, but not required, to use the Expression of Interest template available for download HERE. The template can also be copied as a Google doc with this link.

Contact information

Technical POC: Aman Patel, Special Projects Lead

RFP Email: glycoliser@blueprintbiosecurity.org